Table 1 Concentration and CRLBs of NAD+, NADH, total NAD, and RR at P20, P40, P90, and P250, respectively.
AGE [Days] | GENOTYPE | NAD+ [mM] | CRLB [%] | NADH [mM] | CRLB [%] | RR [-] | TOTAL NAD [mM] |
|---|---|---|---|---|---|---|---|
P20 | WT | 0.38 ± 0.06 | 10 ± 1 | 0.28 ± 0.07 | 11 ± 2 | 1.43 ± 0.47 | 0.66 ± 0.10 |
Gclm-KO | 0.54 ± 0.08 | 9 ± 2 | 0.27 ± 0.09 | 14 ± 3 | 2.28 ± 0.99 | 0.81 ± 0.13 | |
P40 | WT | 0.43 ± 0.13 | 9 ± 2 | 0.23 ± 0.06 | 12 ± 3 | 1.94 ± 0.56 | 0.67 ± 0.18 |
Gclm-KO | 0.46 ± 0.11 | 8 ± 1 | 0.18 ± 0.03 | 13 ± 2 | 2.53 ± 0.70 | 0.64 ± 0.12 | |
P90 | WT | 0.39 ± 0.15 | 10 ± 3 | 0.20 ± 0.06 | 14 ± 3 | 2.15 ± 1.06 | 0.59 ± 0.16 |
Gclm-KO | 0.56 ± 0.12 | 8 ± 2 | 0.16 ± 0.07 | 19 ± 4 | 3.85 ± 1.53 | 0.68 ± 0.12 | |
P250 | WT | 0.42 ± 0.13 | 9 ± 1 | 0.15 ± 0.06 | 19 ± 5 | 3.31 ± 1.55 | 0.57 ± 0.15 |
Gclm-KO | 0.39 ± 0.08 | 11 ± 1 | 0.18 ± 0.04 | 17 ± 3 | 2.31 ± 0.80 | 0.56 ± 0.05 |