Fig. 3: ERSP responses to standard tones and deviants.

The grand average ERSP responses under different stimulus and drug conditions are presented for the TD group (A) and the ASD group (B). The x axis shows the time, and the y axis indicates spectral permutations within the [4, 20] Hz band. Dashed lines indicate the stimulus onsets. C Scatter plots of ERSP responses in [4, 12] Hz are presented for the TD (blue) and ASD (red) group at placebo (top left), 15 mg (top right), and 30 mg (bottom left). The x axis indicates the stimulus conditions. ERSP responses to repeated standards are separately displayed (bottom right) to show the group-drug interaction measured by LMM. The comparisons between stimulus conditions were achieved by paired-sample t test and corrected using the Benjamini–Hochberg method. *, the difference is statistically significant with corrected p < 0.05; **, the difference is statistically significant with corrected p < 0.01. Error bars show SD.