Table 1 Demographic information presented separately for males and females.
From: The impact of placental genomic risk for schizophrenia and birth asphyxia on brain development
Males | Pairwise comparisons | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
HC (n = 467) | SZ (n = 254) | Main effect Group | SZ vs HC | |||||||
ASPH- | ASPH+ | F/χ2 (df) | ASPH- | ASPH+ | F/χ2 (df) | F/χ2 (df) | p | Mean differences (SE) | p | |
Sex, No. Males (%) | 393 (84%) | 74 (16%) | 4.98 (1, 870)a* | 226 (89%) | 28 (11%) | 0.57 (1, 433) | 3.15 (1, 721) | 0.076 b | (HC > SZ) | |
Ancestry, No. non-European (%) | 5 (1%) | 1 (1%) | 0.00 (1, 467) | 31 (14%) | 4 (14%) | 0.00 (1, 254) | 47.89 (1, 721) | < 0.001 | (SZ > HC) | |
Handedness, No. NR (%) | 46 (12%) | 6 (8%) | 0.85 (1, 464) | 31 (15%) | 2 (8%) | 0.92 (1, 230) | 1.41 (1, 694) | 0.235 | - | |
Age, mean years (SD) | 31.71 (7.88) | 30.82 (7.17) | 0.80 (1, 467) | 27.00 (6.55) | 28.14 (6.68) | 0.76 (1, 254) | 59.87 (1, 721) | < 0.001 | −4.45 (0.58) | < 0.001 |
Education, years (SD) | 14.51 (2.32) | 14.16 (2.14) | 1.46 (1, 464) | 12.17 (2.56) | 11.77 (1.68) | 0.61 (1, 231) | 151.33 (1, 695) | < 0.001 | −2.33 (0.19) | < 0.001 |
Adult weight, kg (SD) | 83.73 (12.57) | 83.49 (14.14) | 0.02 (1, 365) | 84.78 (18.71) | 89.55 (18.92) | 1.56 (1, 242) | 1.60 (1, 607) | 0.207 | 1.62 (1.28) | 0.207 |
Adult height, cm (SD) | 182.80 (5.91) | 180.69 (6.04) | 6.39 (1, 367)* | 180.48 (7.06) | 180.07 (7.63) | 0.08 (1, 244) | 14.31 (1, 611) | < 0.001 | −2.02 (0.53) | < 0.001 |
Adult ICV, cm3 (SD) | 1654.71 (114.35) | 1632.20 (109.57) | 2.08 (1, 396) | 1624.09 (122.06) | 1692.82 (121.56) | 2.93 (1, 133) | 3.53 (1, 529) | 0.061 | −21.88 (11.64) | 0.061 |
Gestational age, weeks (SD) | 39.69 (1.86) | 39.81 (2.75) | 0.21 (1, 440) | 39.49 (2.43) | 38.62 (4.38) | 2.44 (1, 237) | 2.79 (1, 677) | 0.095 | −0.31 (0.18) | 0.095 |
Birth weight, grams (SD) | 3595.46 (555.48) | 3555.68 (746.94) | 0.28 (1, 466) | 3545.67 (548.22) | 3287.86 (896.24) | 4.67 (1,253)* | 2.42 (1, 719) | 0.120 | −72.01 (46.31) | 0.120 |
SGA, No. SGA (%) | 48 (13%) | 4 (6%) | 2.74 (1, 439) | 19 (9%) | 5 (19%) | 2.63 (1, 236) | 0.43 (1, 675) | 0.511 | - | |
Neonatal head circumference, cm (SD) | 35.54 (1.57) | 35.35 (1.50) | 0.55 (1, 275) | 35.41 (1.44) | 35.87 (1.64) | 1.37 (1, 175) | 0.17 (1, 450) | 0.685 | −0.06 (0.15) | 0.685 |
Females | Pairwise comparisons | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
HC (n = 403) | SZ (n = 179) | Main effect Group | SZ vs HC | |||||||
ASPH- | ASPH+ | F/χ2 (df) | ASPH- | ASPH+ | F/χ2 (df) | F/χ2 (df) | p | Mean differences (SE) | p | |
Sex, No. Females | 360 (89%) | 43 (11%) | 4.98 (1, 870)a* | 155 (87%) | 24 (13%) | 0.57 (1, 433) | 0.91 (1, 582) | 0.340 | - | |
Ancestry, No. non-European (%) | 8 (2%) | 0 (0%) | 0.98 (1, 402) | 14 (9%) | 4 (17%) | 1.34 (1,179) | 18.85 (1, 581) | < 0.001 | (SZ > HC) | |
Handedness, No. NR (%) | 35 (10%) | 3 (7%) | 0.30 (1, 400) | 17 (12%) | 2 (11%) | 0.01 (1, 159) | 0.75 (1, 559) | 0.388 | - | |
Age, mean years (SD) | 30.97 (7.99) | 28.70 (6.60) | 3.22 (1, 403) | 27.17 (7.21) | 26.42 (6.90) | 0.23 (1, 179) | 28.19 (1, 582) | < 0.001 | −3.65 (0.69) | < 0.001 |
Education, years (SD) | 14.58 (2.09) | 14.60 (2.03) | 0.00 (1, 400) | 12.44 (2.74) | 11.42 (1.61) | 2.49 (1, 159) | 115.39 (1, 559) | < 0.001 | −2.27 (0.21) | < 0.001 |
Adult weight, kg (SD) | 66.47 (10.69) | 65.29 (12.54) | 0.34 (1, 290) | 73.42 (18.13) | 65.83 (11.47) | 3.94 (1, 170)* | 20.62 (1, 460) | < 0.001 | 6.02 (1.33) | < 0.001 |
Adult height, cm (SD) | 168.13 (6.19) | 166.70 (4.47) | 1.65 (1, 292) | 167.40 (5.72) | 167.42 (5.71) | 0.00 (1, 173) | 0.98 (1, 465) | 0.323 | −0.56 (0.57) | 0.323 |
Adult ICV, cm3 (SD) | 1455.92 (94.73) | 1437.40 (84.81) | 1.27 (1, 298) | 1429.52 (118.51) | 1446.44 (104.75) | 0.22 (1, 84) | 3.14 (1, 382) | 0.077 | −21.68 (12.23) | 0.077 |
Gestational age, weeks (SD) | 40.02 (1.57) | 40.41 (1.61) | 2.21 (1, 384) | 39.89 (1.85) | 39.82 (2.72) | 0.03 (1, 167) | 1.37 (1, 551) | 0.242 | −0.19 (0.16) | 0.242 |
Birth weight, grams (SD) | 3454.22 (497.64) | 3383.26 (83.86) | 0.79 (1, 403) | 3469.28 (478.14) | 3334.58 (842.66) | 1.30 (1, 179) | 0.10 (1, 582) | 0.921 | 4.57 (45.81) | 0.921 |
SGA, No. SGA (%) | 38 (11%) | 6 (14%) | 0.37 (1, 384) | 14 (10%) | 5 (23%) | 3.24 (1, 167) | 0.00 (1, 675) | 0.978 | - | |
Neonatal head circumference, cm (SD) | 34.96 (1.31) | 34.91 (1.42) | 0.04 (1, 257) | 34.86 (1.20) | 34.81 (1.64) | 0.02 (1, 122) | 0.50 (1, 379) | 0.481 | −0.10 (0.14) | 0.481 |
