Fig. 5: K252a treatment reversed the anti-depressive activity of eFT508. | Translational Psychiatry

Fig. 5: K252a treatment reversed the anti-depressive activity of eFT508.

From: eIF4E phosphorylation mediated LPS induced depressive-like behaviors via ameliorated neuroinflammation and dendritic loss

Fig. 5

A Drug treatment schedule and experimental approach. B Relative body weight changes. C Sucrose preference test. D Tail suspension test. E Force swimming test. F Open field test. G Grip strength test. H Hanging test and pole test (I). A–E n = 8–11, and F–I n = 8. All the values are expressed as mean ± SEM, one-way ANOVA followed by Turkey’s multiple comparison tests. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.

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