Fig. 2: Pathway enrichment analysis of astrocytes indicating the inhibition of autophagy pathways in patients with MDD. | Translational Psychiatry

Fig. 2: Pathway enrichment analysis of astrocytes indicating the inhibition of autophagy pathways in patients with MDD.

From: Does decreased autophagy and dysregulation of LC3A in astrocytes play a role in major depressive disorder?

Fig. 2: Pathway enrichment analysis of astrocytes indicating the inhibition of autophagy pathways in patients with MDD.

A GSEA pathway enrichment analysis of differentially expressed genes (DEGs) in MDD versus control subjects in astrocytes. B Enrichment plot showing the inhibition of the chaperone-mediated autophagy pathway, selective autophagy pathway, and autophagy pathway. C AUCell analysis showing the inhibition of autophagy pathways in MDD. D Dot plot showing the reduced expression levels of autophagy-related genes in MDD.

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