Table 1 The demographic characteristics of patients with mood disorder.

From: Increased volume of the left hippocampal dentate gyrus after 4 weeks of bright light exposure in patients with mood disorders: a randomized controlled study

 

Patients with mood disorder (n = 24)

p value

BL group (n = 12)

DL group (n = 12)

Age mean (s.d.)

37.7 (12.1)

38.3 (11.4)

0.89

Sex (Male, Female)

6, 6

6, 6

1

Diagnosis

MDD: 7, BP: 5

MDD: 10, BP: 2

0.37

Comorbidity

Panic: 2, SAD:1

Panic: 5, SAD: 2, GAD: 1

 

Psychotropics

Antidepressant:10 (Esci:2, Mirt:2, Sert:1, Paro:2, Dulo:1, Venl:1, Traz:1), Mood stabilizer:6 (LTG:3, Li:3), Antipsychotics:7 (QUE:4, ARI:1, LEV:2), Hypnotics:9

Antidepressant:16 (Esci:4, Dulo:3, Mirt:6, Sert:1, Paro:1, Dosu:1), Mood stabilizer:7 (LTG:4, Li:2, VPA:1), Antipsychotics:6 (QUE:2, ARI:2, OLA:1, SUL:1), Hypnotics:10

 

Season

Spring:1, Summer:4, Autumn:4, Winter:3

Spring:1, Summer:3, Autumn:3, Winter:5

0.85

Environmental light (s.d.) lux

168.3 (60.1)

129.8 (52.2)

0.11

Log-transformed environmental light (s.d.)

2.20 (0.17)

2.08 (0.20)

0.11

HAM-D (s.d.)

9.1 (3.6)

9.83 (4.0)

0.64

BDI (s.d.)

18.6 (10.9)

20.9 (10.0)

0.59

YMRS (s.d.)

1.3 (1.4)

1.0 (1.0)

0.62

VAS of mood (s.d.)

45.5 (13.8)

42.5 (15.2)

0.62

DG Volume mm3 mean (s.d.)

Left DG-head

153.5 (23.0)

156.1 (17.9)

0.76

Left DG-body

131.8 (14.9)

132.0 (20.9)

0.98

Left DG-total

285.3 (33.4)

288.2 (34.2)

0.84

Right DG-head

161.0 (21.4)

158.9 (15.3)

0.77

Right DG-body

139.1 (17.7)

132.5 (17.6)

0.37

Right DG-total

300.3 (35.3)

291.4 (25.5)

0.49

  1. ARI Aripiprazole, BDI Beck Depression Inventory, BP bipolar disorder, BL group Bright light exposure group, DG dentate gyrus, DL group Dim light exposure group, Dosu Dosulepin, Dulo Duloxetine, Esci Escitalopram, GAD Generalized anxiety disorder, HAM-D Hamilton Depression Rating Scale, MDD Major Depressive Disorder, Mirt Mirtazapine, LEV Levomepromazine, Li Lithium, LTG Lamotrigine, OLA Olanzapine, Panic panic disorder, Paro paroxetine, QUE Quetiapine, Sert Sertraline, SUL sulpiride, SAD social anxiety disorder, s.d. standard deviation, Traz Trazodone, VPA Valproate, Venl Venlafaxine, VAS Visual Analog Scale, YMRS Young Mania Rating Scale.