Fig. 2: Effects on affective empathy following DBS. | Translational Psychiatry

Fig. 2: Effects on affective empathy following DBS.

From: Normalized affective responsiveness following deep brain stimulation of the medial forebrain bundle in depression

Fig. 2

Shown are mean scores of differences in affect rating between negative and neutral situations (i.e. affective responsiveness) in patients with treatment-resistant depression (TRD, n = 12; in grey) and healthy control subjects (HC, n = 12; in white). Error bars represent 95% confidence intervals. Asteriks indicate a statistically significant difference (p ≤ 0.05, two-sided). Small dots represent individual data points. A Change of affective responsiveness from baseline to follow-up (difference follow-up – baseline) differed significantly between TRD patients in comparison to HC (p = 0.05). B Affective responsiveness scores separately displayed for baseline (left side) and follow-up (right side). At baseline, patients with TRD experienced significantly reduced affective responsiveness compared to HC. At follow-up no difference between the groups was found indicating a normalized affective responsiveness in patients with TRD after three months of active slMFB DBS. n.s. not significant.

Back to article page