Fig. 3: Prospective association of CAZymes markers with severity.

a, b Prospective association of baseline gut CAZymes with HAMD and QIDS score. A total of 45 participants were included in this analysis. Linear mixed-effects model was performed to assess the prospective association of gut CAZymes with the clinical score, adjusting for the demographic (age, gender and educational background), anthropometric (BMI), times of depressive episode and medication. A p-value < 0.05 was considered as statistically significant (estimated value β, 95%CI).