Table 1 SNP heritability (variability of lifetime depression status accounted for by the whole set of SNPs) within each cluster.

From: Olfactory genes affect major depression in highly educated, emotionally stable, lean women: a bridge between animal models and precision medicine

Cluster

SNP h2

Lower 95% CI of SNP h2

Upper 95% CI of SNP h2

Intercept (SE)

Ratio (SE)

male risk cluster

0.0252

0.013832

0.036568

0.9974 (0.0068)

<0

male protective cluster

0.022

0.006516

0.037484

1.01 (0.0069)

0.2491 (0.1704)

female risk cluster

0.0277

0.01888

0.03652

1.0029 (0.0069)

0.0432 (0.1035)

female protective cluster

0.0329

0.018788

0.047012

1.0035 (0.0063)

0.0768 (0.1386)

  1. Intercept and ratio from the LD Score Regression model are also shown. The expected value for intercept is <1.10; and for ratio is a maximum of 10–20%.
  2. SNP single-nucleotide polymorphism, h2 heritability, CI confidence interval, SE standard error, LD linkage disequilibrium.
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