Table 1 Subject characteristics.

From: Distinct saliva DNA methylation profiles in relation to treatment outcome in youth with posttraumatic stress disorder

 

Responders (n = 22)

Non-responders (n = 24)

Controls (n = 41)

p-valuea

Sociodemographic characteristics

Female (%)

40.9

67.7

53.7

0.215

Age (years; mean, SD)

12.09 (3.07)

12.92 (2.74)

11.70 (3.81)

0.379

West European Ethnicity (%)

73.7

47.8

85.4

0.006

Trauma characteristics

Index trauma (%)

   

0.000*

Sexual abuse

22.7

20.8

0

Interpersonal violence

36.4

50.0

19.5

Accidents/Medical

13.6

12.5

61.0

Other

27.3

16.7

19.5

Repeated trauma exposure (%)

59.1

58.3

22.0

0.002*

Clinical characteristics

CAPS-CA study entry T1 (mean, SD)b

51.14 (23.0)

47.75 (22.61)

-

0.170

CAPS-CA post treatment T2 (mean, SD)b

19.82 (16.14)

45.50 (21.48)

-

0.000*

CAPS-CA Follow-up treatment T3 (mean, SD)b

9.09 (7.80)

46.14 (19.1)

-

 

Externalizing problem behavior T1 (%)c

53.3

20.0

26.7

0.037*

Internalizing problem behavior T1 (%)c

57.1

35.7

7.1

0.002*

  1. CAPS-CA Clinician-Administered PTSD Scale for Children and Adolescents,
  2. ap-values < 0.05 shown in bold. Independent samples t-test for continuous and x2 tests for categorical variables.
  3. bRange: CAPS-CA total, 0–139,
  4. cInternalizing and Externalizing behavior are reported if a child scored above clinical cut-off on the RCADS/ YSR and SDQ RCADS, Revised Child Anxiety and Depression Scale. *indicates a significant result.
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