Table 4 Correlations between cortisol secretion and CRHR2 methylation.

From: Distinct saliva DNA methylation profiles in relation to treatment outcome in youth with posttraumatic stress disorder

 

cg18090898 (CRHR2) Total sample

cg18090898 (CRHR2) Responders

cg18090898 (CRHR2) Non-Responders

Pretreatment cortisol

−0.395*

−0.173

0.127

Posttreatment cortisol

−0.458*

−0.446*

0.439*

CAPS score Total T1

0.369*

0.471*

−0.122

Total score Cluster B T1

0.323

0.264

0.201

Total score Cluster C T1

0.088

0.222

−0.071

Total score Cluster D T1

0.446*

0.072

0.534*

  1. CAPS-CA Clinician-Administered PTSD Scale for Children and Adolescents Pearson’s correlations between individual beta’s on selected DMP and cortisol secretion data in youth with PTSD and different clusters of PTSD symptoms and cortisol levels before and after trauma-focused psychotherapy. *Correlation is significant at the 0.05 level (2-tailed).