Fig. 1: Stress-susceptible mice show increased hippocampal H1x protein expression following chronic social defeat. | Translational Psychiatry

Fig. 1: Stress-susceptible mice show increased hippocampal H1x protein expression following chronic social defeat.

From: Histone H1x in mouse ventral hippocampus associates with, but does not cause behavioral adaptations to stress

Fig. 1

A Experimental timeline detailing 10-day chronic social defeat stress paradigm. B Stress-susceptible mice (n = 18) show significant decrease in social interaction ratio compared to single housed mice (n = 10) and stress-resilient (n = 12) mice. (One-way ANOVA with Bonferroni’s correction, **: p = 0.0053) (C) Western blot analysis shows ventral hippocampus tissue from susceptible brains express significantly higher H1x protein levels compared to single housed control brains, while resilient brains do not. (One-way ANOVA with Bonferroni’s correction, ***: p = 0.0010).

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