Fig. 2: RNA sequencing analysis for exploring DEGs and signaling pathways in the hippocampal expressional profiles of mice in the CD group, HFD group (with and without 1-MT treatment). | Translational Psychiatry

Fig. 2: RNA sequencing analysis for exploring DEGs and signaling pathways in the hippocampal expressional profiles of mice in the CD group, HFD group (with and without 1-MT treatment).

From: 1-Methyltryptophan treatment ameliorates high-fat diet-induced depression in mice through reversing changes in perineuronal nets

Fig. 2

A DEGs between the CD and HFD groups. B DEGs between the HFD group and the HFD group treated with 1-MT. C Genes cross-referenced between the CD group, HFD group, and HFD group treated with 1-MT. D Pathway enrichment analysis of 130 shared differential genes. E Relative mRNA expression of the nine identified ECM regulators in the CD group, HFD group, and HFD group treated with 1-MT. Error bars represent the standard error of the mean. N = 3 for each group. 1-MT 1-methyltryptophan, CD chow diet, ECM extracellular matrix, HFD high-fat diet.

Back to article page