Fig. 2: SMAASH-C blunts cocaine/abstinence induced toxicity in males following a two-week treatment regimen. | Translational Psychiatry

Fig. 2: SMAASH-C blunts cocaine/abstinence induced toxicity in males following a two-week treatment regimen.

From: Impact of SMAASH-C, a novel nutritional supplement, on drug-seeking and toxicity in female and male rats

Fig. 2

A Experimental summary: Serum was collected the morning after extinction/reinstatement testing from a subset of rats in the control-chow (n = 13 males, 10 females), 0.4 g/kg SMAASH-C (n = 11 males, 11 females), and 0.8 g/kg SMAASH-C (n = 8 males, 8 females) treatment (Tx) groups as well as from additional groups of control-chow rats given access to saline (Sal) rather than cocaine during acquisition and the extended-access (ExA) phase (n = 5 males and n = 6 females). B Serum concentration of aspartate transaminase (AST; B), alanine transaminase (ALT, C), and amylase (D) for each of the female (left panels) and male (right panels) rats in the control-chow and 0.4 and 0.8 g/kg SMAASH-C groups. Solid black bars represent group means. ^Significant difference from saline (B). #Significant effect of SMAASH-C (B). *Significant effect of sex (D).

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