Fig. 5: A summary of the behavioral and toxicity findings across both experiments. Mean (±SEM) percent difference from the 2-week.

Mean (±SEM) percent difference from the 2-week (A) and control-chow (B) group for cocaine-seeking (responses during hour one of extinction plus reinstatement), and from the saline control group for serum levels of aspartate transaminase (AST; C), alanine transaminase (ALT, D), and amylase (E). +Significant difference from 2-weeks (A, C, E). #Significant effect of SMAASH-C (B, C, E). ^Significant difference from saline (or 0; C–E).