Table 2 The areas of significantly different FC between the MDD patients and the HCs (voxel p < 0.005, cluster p < 0.006, GRF corrected).

From: Gut proinflammatory bacteria is associated with abnormal functional connectivity of hippocampus in unmedicated patients with major depressive disorder

Subregions

Location in the cerebrum

MNI coordinates

Peak t value

Cluster size (voxel numbers)

X

Y

Z

L CA2

R caudal hippocampus (mainly CA2 and CA3)

33

-33

0

4.48

64

L CA3

R caudal hippocampus (mainly CA2 and CA3)

33

-30

-3

5.16

68

L DG

R caudal hippocampus (mainly CA2 and CA3)

33

-33

0

5.33

79

R CA3

L PCC

-3

-48

30

-3.58

51

  1. FC functional connectivity, MDD major depressive disorder, HCs healthy controls, GRF Gaussian random field, CA cornu ammonis, PCC posterior cingulate cortex, L (R) left (right) hemisphere.
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