Fig. 3: Effects of oxytocin and nicotine addiction on psychosocial stress in anterior superior temporal gyrus.
From: The interaction of oxytocin and nicotine addiction on psychosocial stress: an fMRI study
Changes in anterior right superior temporal gyrus (rSTG) activation in stress runs 1 and 2 (A). The changes in beta estimates of the anterior rSTG in stress run 2 were inversely correlated with an index of nicotine addiction after PLC administration (B). In the HC group, changes in beta estimates of the anterior rSTG were positively associated with changes in salivary cortisol after the administration of PLC in stress run 2 (C). In the SMO group, between-run changes in beta estimates of the anterior rSTG were inversely correlated with an index of nicotine addiction after PLC administration (D). Between-runs changes in the beta value of the anterior rSTG were positively associated with changes in subjective stress ratings after administration of PLC, which was significantly differently directed in the SMO group (E). HC: healthy participants group (n = 27); SMO: smoker group (n = 26); PLC: placebo; OXT: oxytocin; *p < 0.05; **p < 0.01.
