Fig. 3: WT mice exposed to a rich social environment display improved social skills. | Translational Psychiatry

Fig. 3: WT mice exposed to a rich social environment display improved social skills.

From: Effect of the social environment on olfaction and social skills in wild-type and a mouse model of autism

Fig. 3

In the Live Mouse Tracker, WT male and female mice raised in groups of 4 animals (dark gray; n = 46, 19 males and 27 females) displayed constant time in nose contacts (A), huddling (B), social approach (C), ‘move in contact’ (D) and isolated (E) across trials. In contrast, animals raised in groups of 2 (light gray; n = 18, 9 males and 9 females) and 3 (middle gray; n = 33, 27 males and 6 females) spent less time in these parameters over consecutive trials. F Regardless of housing conditions, mice spent more time in the periphery as the number of trials increased. Data are presented as mean ± sd (Table S3). Robust linear model followed by pairwise comparisons using the estimated marginal means, with stars as trial effect and hash as housing effect (p = P adjusted in all tests). * or #: p < 0.05, ** or ##: p < 0.01, *** or ###: p < 0.001, **** or ####: p < 0.0001.

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