Fig. 1: Overview of the study scheme. | Translational Psychiatry

Fig. 1: Overview of the study scheme.

From: Disorder-specific neurodynamic features in schizophrenia inferred by neurodynamic embedded contrastive variational autoencoder model

Fig. 1: Overview of the study scheme.

a Neurodynamic embedded contrastive variational autoencoder (ND-CVAE) Model. Shared and SCZ-specific features were extracted from two encoders and used to construct the source model of brain dynamics. b Evaluations and comparisons of shared and SCZ-specific features, including subject-level parameters \({{\boldsymbol{\theta }}}^{{\rm{s}}}\), region-level parameters \({{\boldsymbol{\theta }}}^{{\rm{r}}}\), and the hidden states of node systems \({\boldsymbol{x}}\). c Neurodynamic-clinic association analysis. The relationship between the encoded features and participant properties were mapped via PLS regression. The underlying potential micro-transcriptomic mechanisms were explored by transcription association analyses.

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