Table 2 Significant loci identified by genome-wide analyses.
SNP | CHR | BP | A1 | BETA | P | Hit gene | Tissue specificity (LifeMap Discovery & GTEx v8) | Psychiatric or digestive disorders-related phenotype associations |
|---|---|---|---|---|---|---|---|---|
rs10880574 | 12 | 44235427 | G | −0.5134 | 2.39E-09 | TMEM117 | Brain (Myelinating Oligodendrocyte cells), and others. | Electroencephalogram measurement [56]; inflammatory bowel disease [58] |
rs2000900 | 18 | 47502338 | T | −0.4648 | 3.31E-09 | MYO5B | Esophagus, minor Salivary gland, colon, intestine; liver; kidney; intestine; adipose, and others. |