Fig. 1: Activation of thalamic nucleus reuniens in different induced grooming behaviors in rats.
From: The midline thalamic nucleus reuniens promotes compulsive-like grooming in rodents
A Rats subjected to ACTH i.c.v. infusion, body restraint, or fur-moistening through swimming (n = 3 in each group) demonstrated increased grooming compared with spontaneous grooming level (n = 4). One-way ANOVA: effect of treatment on grooming duration: F(3,9) = 9.282, p = 0.0041. Post-hoc Tukey HSD test; *p < 0.05, **p < 0.01, compared with spontaneous condition. B Representative images showing c-Fos+ neurons in the NRe following various grooming-inducing models. Scale bar, 100 µm. C c-Fos immunostaining revealed increased activation of NRe neurons after rats exhibited elevated grooming behavior induced by various stressors. One-way ANOVA: effect of treatment on c-Fos expression level: F(3,9) = 8.660, p = 0.0051. Post-hoc Tukey HSD test; *p < 0.05, **p < 0.01, compared with spontaneous condition. All data are presented as mean ± SEM.
