Table 2 Main effects models for association between the presence of MetS and current depressive symptom severity (total PHQ-9 scores), current depressive symptoms (yes/no), and antidepressant use.

From: Increased odds of metabolic syndrome among adults with depressive symptoms or antidepressant use

MetS (yes/no)

Exposure group

OR (95% CI)

p-value

aOR (95% CI)

p-value

Total PHQ-9 scores1a

1.05 (1.04, 1.06)

<0.001

1.04 (1.02, 1.05)

<0.001

Antidepressant use - yes1b

1.70 (1.46, 1.97)

<0.001

1.24 (1.03, 1.50)

0.025

Depressive symptoms - yes2a

1.78 (1.51, 2.10)

<0.001

1.42 (1.17, 1.73)

0.001

Antidepressant use - yes2b

1.70 (1.46, 1.97)

<0.001

1.31 (1.09, 1.57)

0.004

  1. OR unadjusted odds ratio, aOR adjusted odds ratio, CI confidence interval, the reference level for depressive symptoms is “no”. 1aCovariates in adjusted models include all 15 pre-selected covariates and antidepressant use. 1bCovariates in adjusted models include all 15 pre-selected covariates and depressive symptom severity (total PHQ-9 scores). 2aCovariates in adjusted models include all 15 pre-selected covariates and antidepressant use. 2bCovariates in adjusted models include all 15 pre-selected covariates and depressive symptoms (yes/no). p-values < 0.05 denote statistical significance.
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