Table 1 Characteristics of demographic and clinical variables.

From: Family history, inflammation, and cerebellum in major depression: a combined VBM and dynamic functional connectivity study

Variables

HC (96)

NFH (91)

FH (43)

p-value

Age (years)

23.21 ± 6.08

23.3 ± 11.79

26.79 ± 13.6

0.13a

Gender (male/female)

44/52

30/61

21/22

0.11b

Education (years)

14.58 ± 3.37

10.35 ± 3.82

11.44 ± 3.91

< 0.0001a

Mean FD (mm)

0.06 ± 0.04

0.07 ± 0.05

0.07 ± 0.05

0.06a

Duration of illness (months)

—

32.33 ± 32.55

49.5 ± 44.85

< 0.05c

Age of onset (years)

—

21.44 ± 11.63

23.56 ± 12.76

0.39c

Number of depressive episodes

—

3.64 ± 7.39

3.0 ± 3.18

0.42c

HAMD score

—

35.77 ± 13.1

33.71 ± 15.64

0.46c

CRP (mg/L)

—

0.61 ± 0.81

1.05 ± 1.54

0.12c

IL-6 (pg/mL)

—

2.28 ± 3.41

2.47 ± 2.17

0.78c

  1. Values are mean ± SD.
  2. HC healthy control, NFH major depressive disorder without family history, FH major depressive disorder with a first-degree family history, HAMD Hamilton Depression Scale, CRP C-reaction protein, IL-6 interleukin-6.
  3. aOne-way analysis of variance.
  4. bChi-square t-test.
  5. cTwo-sample t-test.
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