Fig. 4: Partial mediation effect of PSMD between CPV and MMSE in both cross-sectionally and longitudinally.

A The PSMD partially mediated the association between CPV and cognitive function. B The PSMD partially mediated the association between CPV and cognitive progress. CP choroid plexus, PSMD peak width of skeletonized mean diffusivity, MMSE Mini-Mental State Examination.