Fig. 2: Increased Aβ plaques induced by ethanol exposure in APP/PS1 mice. | Translational Psychiatry

Fig. 2: Increased Aβ plaques induced by ethanol exposure in APP/PS1 mice.

From: N-acetylcysteine (NAC) ameliorates ethanol-induced oxidative stress, neuroinflammation, and cognitive dysfunction in APP/PS1 mouse model

Fig. 2

A–C Representative images of Aβ plaques immunohistochemistry (IHC) results in the hippocampus and cortex of 4-week, 8-week, and 10-week ethanol-exposed WT and APP/PS1 mice. No Aβ deposition was found in either WT or APP/PS1 mice after 4-week ethanol exposure, while the Aβ depositions appeared in the cortex and hippocampus of 8-week and 10-week ethanol-exposed APP/PS1 mice. Yellow triangle indicated Aβ plaque, scale bar = 500 μm, each group contained three mice.

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