Fig. 6: NAC treatment may partially restore ethanol exposure induced neuroinflammatory impairments in APP/PS1 mice. | Translational Psychiatry

Fig. 6: NAC treatment may partially restore ethanol exposure induced neuroinflammatory impairments in APP/PS1 mice.

From: N-acetylcysteine (NAC) ameliorates ethanol-induced oxidative stress, neuroinflammation, and cognitive dysfunction in APP/PS1 mouse model

Fig. 6

A Representative images of Iba1 immunofluorescence results in the 10-week ethanol-exposed mice. And the Iba1+ was increased in ethanol exposure group in APP/PS1 mice and can be partially restored after NAC co-treatment. Western blot revealed that the elevated TNF-α (B), and reduced SYP (C), PSD95 (D), and BDNF (E) protein levels induced by ethanol exposure in APP/PS1 mice can be partially restored after NAC co-treatment. Each group contains three mice, *p < 0.05, **p < 0.01.

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