Fig. 2: Changes in Epigenetic Biomarkers of Aging Before and After Ketamine Treatment Course.

A OMICmAge. B GrimAge V2. C PhenoAge. D CD4 Memory T-cells. The y-axis shows the epigenetic age acceleration (EAA) for each biomarker of aging and the immune cell proportion of CD4 Memory T-cells. The x-axis represents the timepoints for treatment with ketamine. Each color corresponds to one patient, with a line connecting their predicted marker from baseline to post-treatment. Colors across panels also correspond to the same individual. P-values reported are unadjusted.