Table 3 Group comparisons of volume across 7 subcortical regions (each hemisphere) between OCD and healthy controls.

From: Widespread alterations of white matter integrity in medication-free obsessive-compulsive disorder

Subcortical Region

Hemisphere

OCD

HC

Group difference

  

Mean ± SD

Mean ± SD

F

p_fdr

Thalamus

L

8769.17 ± 879.60

8225.68 ± 820.70

2.759

0.172

R

8803.33 ± 874.86

8228.26 ± 661.84

4.937

0.087

Caudate

L

3733.12 ± 458.31

3718.39 ± 434.62

2.568

0.172

R

3746.14 ± 479.96

3793.59 ± 442.05

4.796

0.087

Putamen

L

5616.97 ± 534.28

5337.84 ± 583.62

0.688

0.477

R

5736.23 ± 551.38

5520.06 ± 649.18

0.016

0.954

Pallidum

L

2233.67 ± 278.71

2090.83 ± 270.81

2.144

0.187

R

2129.34 ± 243.24

1998.56 ± 213.97

2.425

0.172

Hippocampus

L

4423.37 ± 334.50

4116.57 ± 357.77

10.225

0.009

R

4691.29 ± 385.40

4435.64 ± 359.25

3.370

0.140

Amygdala

L

1876.71 ± 215.27

1687.32 ± 156.54

12.985

0.007

R

1984.32 ± 207.30

1746.22 ± 147.72

27.269

<0.001

Nucleus Accumbens

L

465.51 ± 79.41

448.55 ± 90.08

0.003

0.954

R

580.41 ± 88.34

528.51 ± 90.65

3.858

0.124

  1. P values were corrected for multiple comparisons using the false discovery rate (FDR) method. Significant increased subcortical volumes in OCD group (p_fdr < 0.05) were marked in bold.
  2. HC healthy control, L left hemisphere, R right hemisphere.