Table 3 Top 10 DMRs associated with ECTresp (percent response or remission) in the Norwegian cohort, across timepoints or at baseline.

From: Epigenetic and blood markers associated with response to electroconvulsive therapy in patients with depressive disorders

chromosome

start

end

min_p

n_probes

z_p

z_sidak_p

genes

Percent response across timepoints

8

1765217

1765820

5.491E-19

8

1.465E-27

1.616E-24

MIR596

6

31691198

31692260

1.608E-16

24

2.11E-24

1.322E-21

MPIG6B

15

75019070

75019376

1.464E-11

10

7.77E-16

1.69E-12

CYP1A1

2

206628415

206628773

1.047E-08

9

1.201E-11

2.232E-08

NRP2

1

67600547

67600835

9.595E-08

5

1.03E-11

2.38E-08

C1orf141

1

236686564

236686988

9.601E-07

10

1.266E-10

1.986E-07

LGALS8; LGALS8-AS1

17

40274524

40274811

6.815E-07

7

9.269E-11

2.149E-07

HSPB9; KAT2A

10

695844

696063

5.046E-06

5

4.778E-10

1.451E-06

DIP2C; C10orf108

4

25090491

25090665

1.15E-05

4

1.228E-09

4.694E-06

 

4

99851003

99851281

1.617E-05

7

2.652E-09

6.348E-06

EIF4E

Remission across timepoints

2

206628355

206628773

5.406E-25

10

7.416E-29

1.18E-25

NRP2

3

185911316

185912253

3.338E-12

6

2.579E-21

1.831E-18

DGKG

17

8702369

8702896

9.381E-14

8

8.307E-18

1.049E-14

MFSD6L

18

74799250

74799572

6.076E-12

4

1.808E-16

4.587E-13

MBP

6

31691354

31692026

1.962E-09

18

4.428E-15

4.397E-12

MPIG6B

10

14372108

14372913

3.449E-05

5

1.053E-13

8.699E-11

FRMD4A

1

223566447

223566794

5.052E-10

7

3.332E-12

6.388E-09

C1orf65; CCDC185

2

9613721

9614052

3.366E-08

5

3.18E-12

6.392E-09

IAH1

5

476405

476646

1.922E-08

3

1.729E-11

4.773E-08

SLC9A3; LOC100288152

18

14748040

14748298

3.606E-08

7

6.964E-11

1.796E-07

ANKRD30B

Percent response at baseline

6

31691198

31691812

3.677E-07

17

5.242E-12

5.68E-09

MPIG6B

8

1765217

1765477

3.35E-07

6

2.96E-12

7.574E-09

MIR596

Remission at baseline

18

74799250

74799572

1.573E-10

4

6.413E-16

1.376E-12

MFSD6L

5

178986372

178986830

3.391E-08

11

4.682E-13

6.801E-10

RUFY1

17

8702698

8702896

1.597E-07

5

1.784E-09

5.994E-06

MFSD6L

6

31691506

31691870

0.0001203

9

2.652E-07

0.0004846

MPIG6B

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