Table 4 Association of immune cell type proportions with ECTexp and ECTresp (percent or remission).

From: Epigenetic and blood markers associated with response to electroconvulsive therapy in patients with depressive disorders

 

Percent response

ECTexp

Percent response x ECTexp interaction

Cell type

Estimate

SE

P-value

Estimate

SE

P-value

Estimate

SE

P-value

NLR

5.57E-03

2.78E-03

5.03E-02

1.04E-01

8.05E-02

2.01E-01

-3.30E-03

3.07E-03

2.86E-01

CD4T

−1.11E-04

2.30E-04

6.30E-01

−7.78E-03

6.54E-03

2.38E-01

2.64E-04

2.49E-04

2.92E-01

CD8T

−4.09E-04

1.91E-04

3.68E-02

−4.80E-03

3.39E-03

1.61E-01

2.31E-05

1.20E-04

8.48E-01

Neu

8.66E-04

4.31E-04

4.96E-02

1.82E-02

1.25E-02

1.48E-01

-5.15E-04

4.74E-04

2.82E-01

Mono

−9.01E-05

1.24E-04

4.71E-01

−6.33E-04

2.74E-03

8.18E-01

1.08E-04

1.00E-04

2.87E-01

Bcell

−1.22E-04

8.27E-05

1.44E-01

−3.58E-03

1.78E-03

4.69E-02

8.52E-05

6.44E-05

1.91E-01

NK

−1.26E-04

1.05E-04

2.39E-01

−7.28E-04

3.30E-03

8.26E-01

7.38E-05

1.28E-04

5.65E-01

 

Remission

ECTexp

Remission x ECTexp interaction

Cell type

Estimate

SE

P-value

Estimate

SE

P-value

Estimate

SE

P-value

NLR

3.86E-01

1.26E-01

3.36E-03

1.03E-01

8.04E-02

2.04E-01

−2.26E-01

1.55E-01

1.48E-01

CD4T

−1.08E-02

1.08E-02

3.21E-01

−7.79E-03

6.54E-03

2.37E-01

1.68E-02

1.25E-02

1.86E-01

CD8T

−1.81E-02

9.19E-03

5.34E-02

−4.79E-03

3.39E-03

1.61E-01

3.44E-03

6.08E-03

5.74E-01

Neu

6.31E-02

1.93E-02

1.89E-03

1.80E-02

1.24E-02

1.51E-01

−3.36E-02

2.40E-02

1.66E-01

Mono

−1.49E-02

5.61E-03

1.02E-02

−7.13E-04

2.71E-03

7.93E-01

8.59E-03

5.01E-03

9.15E-02

Bcell

−7.87E-03

3.86E-03

4.62E-02

−3.60E-03

1.77E-03

4.56E-02

3.48E-03

3.29E-03

2.95E-01

NK

−1.17E-02

4.80E-03

1.81E-02

−7.22E-04

3.30E-03

8.27E-01

3.82E-03

6.48E-03

5.57E-01

  1. *NLR neutrophil-to-lymphocyte ratio, CD4T CD4 + T-cells, CD8 CD8 + T-cells, Neu neutrophils, Mono monocytes, Bcell B-cells, NK natural killer cells.
  2. Significant associations are highlighted in bold.