Table 6 DMRs associated with ECTresp (delta score or binary response) in the meta-analysis.

From: Epigenetic and blood markers associated with response to electroconvulsive therapy in patients with depressive disorders

chromosome

start

end

min_p

n_probes

z_p

z_sidak_p

genes

Delta score across timepoints

15

75019070

75019376

8.30E-12

10

1.25E-16

2.19E-13

CYP1A1

8

1765217

1765477

5.97E-11

5

1.48E-15

3.35E-12

MIR596

10

695844

696063

3.89E-09

5

1.16E-13

3.20E-10

DIP2C;C10orf108

1

67600547

67600963

1.35E-07

6

8.09E-12

1.17E-08

C1orf141

21

42741788

42742432

0.0001837

5

2.77E-11

2.59E-08

MX2

13

112986154

112986978

0.005391

4

8.75E-11

6.40E-08

 

11

44978644

44979029

5.98E-07

4

7.06E-11

1.11E-07

 

8

1321333

1321883

0.00175

5

4.83E-10

5.30E-07

 

6

291687

292596

0.01001

7

1.09E-09

7.23E-07

DUSP22

21

39644216

39644354

3.93E-06

6

2.28E-10

9.96E-07

KCNJ15

Binary response across timepoints

6

291687

292596

6.33E-07

8

3.44E-19

2.28E-16

DUSP22

8

1765217

1765477

8.23E-13

5

6.47E-18

1.50E-14

MIR596

19

50666238

50666552

5.67E-11

5

1.47E-15

2.77E-12

C19orf41

6

31691198

31692026

1.09E-06

18

7.54E-12

5.49E-09

C6orf25

2

43295303

43295595

2.55E-07

4

1.02E-11

2.10E-08

 

6

168785320

168785524

4.57E-07

4

9.86E-12

2.92E-08

 

11

44978644

44979029

5.66E-07

4

4.03E-11

6.31E-08

 

1

67600547

67600835

6.98E-07

5

4.20E-11

8.79E-08

C1orf141

12

2944163

2944493

5.21E-06

8

3.83E-10

6.99E-07

NRIP2

7

123198201

123198553

1.02E-05

6

8.50E-10

1.46E-06

NDUFA5

Delta score baseline

2

3699195

3699353

3.93E-07

4

6.27E-12

2.39E-08

 

Binary response baseline

2

3699195

3699563

1.24E-08

5

7.74E-14

1.27E-10

 

6

291687

292522

0.0002098

6

3.23E-13

2.33E-10

DUSP22

8

144660772

144661051

3.07E-07

5

4.22E-12

9.13E-09

NAPRT1;NAPRT

22

38092771

38092989

6.48E-05

5

5.71E-07

0.001579

TRIOBP

  1. The Top 10 are displayed for analyses across timepoints, the significant DMPs are displayed for baseline.