Table 2 Associations between Family History of Autism and ADHD and Trajectories of Sensory Hyper-Responsivity (Model 1a).

From: Cortical markers of excitation/inhibition balance are associated with sensory responsivity from infancy in longitudinal cohorts enriched for autism and ADHD

 

b

95% CI

p

B

Hyper-responsivity intercept

FH-Autism

1.385

−2.992

5.762

0.535

0.059

FH-ADHD

1.895

−2.583

6.372

0.407

0.079

FH-Autism*FH-ADHD

3.036

−5.945

12.018

0.508

0.091

Sex

−0.920

−4.910

3.070

0.651

−0.041

Hyper-responsivity slope

FH-Autism

1.936

0.153

3.720

0.033

0.256

FH-ADHD

1.197

−0.636

3.029

0.201

0.154

FH-Autism*FH-ADHD

−1.055

−4.730

2.619

0.574

−0.098

Sex

−0.503

−2.138

1.132

0.546

−0.069

36m SRS Total

Hyper-responsivity intercept

0.035

0.026

0.045

0.000

0.587

Hyper-responsivity slope

0.081

0.047

0.114

0.000

0.434

FH-Autism

0.158

−0.048

0.365

0.133

0.113

FH-ADHD

0.065

−0.140

0.270

0.533

0.045

FH-Autism*FH-ADHD

−0.004

−0.408

0.400

0.985

−0.002

Sex

−0.038

−0.216

0.140

0.676

−0.028

36m CBCL ADHD Total

Hyper-responsivity intercept

0.183

0.134

0.231

0.000

0.603

Hyper-responsivity slope

0.332

0.164

0.500

0.000

0.355

FH-Autism

0.212

−0.827

1.252

0.689

0.030

FH-ADHD

0.598

−0.444

1.640

0.261

0.082

FH-Autism*FH-ADHD

−0.586

−2.633

1.462

0.575

−0.058

Sex

−0.444

−1.347

0.460

0.336

−0.065

  1. FH-Autism*FH-ADHD terms were added in a separate step so FH-Autism and FH-ADHD terms should be interpreted as direct effects.
  2. CBCL child behavior checklist, FH family history, SRS social responsiveness scale.