Table 1 Correlation between the ghrelin/LEAP2 ratio and EDI-2 (total score and subscores) after weight restoration in patients with AN.

From: The role of LEAP2 on cognitive impulsivity after refeeding: evidence from a preclinical study in female mice and from patients with anorexia nervosa

Correlation with ghrelin/LEAP2 molar ratio

All (n = 30)

Stable weight gain (n = 14)

Unstable weight gain (n = 16)

Spearman’s r

p-value

Spearman’s r

p-value

Spearman’s r

p-value

Age

0.149

0.433

−0.146

0.616

0.269

0.313

Body mass index

−0.263

0.160

0.001

0.999

−0.330

0.210

EDI-2 total

−0.172

0.364

−0.271

0.346

−0.109

0.686

 Drive for thinness

−0.067

0.724

−0.347

0.223

0.178

0.505

 Bulimia

0.001

0.998

−0.066

0.822

0.252

0.500

 Body dissatisfaction

0.057

0.766

−0.049

0.869

0.186

0.488

 Ineffectiveness

−0.024

0.898

−0.046

0.875

0.056

0.836

 Perfectionnism

−0.256

0.172

−0.137

0.639

−0.341

0.195

 Interpersonal Distrust

−0.027

0.887

−0.059

0.840

−0.076

0.779

 Interoceptive awarness

−0.267

0.154

−0.301

0.293

−0.279

0.292

 Maturity fear

−0.202

0.285

−0.460

0.099

−0.029

0.915

 Ascitism

−0.164

0.387

−0.207

0.473

−0.126

0.643

 Impulse regulation

−0.353

0.056

−0.573

0.035

−0.134

0.618

 Social insecurity

−0.160

0.397

−0.161

0.579

−0.096

0.722

  1. 30 female patients were evaluated after weight restoration based on their remission status (stable or unstable weight gain) 6 months after discharge. Data are expressed as Spearman’s r coefficient and p-value. EDI-2: Eating Disorder Inventory-2. Significant correlations are indicated in bold.
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