Fig. 3: GO/KEGG pathway enrichment analysis of DEGs.
From: 4-Methoxydalbergione is a potent inhibitor of human astroglioma U87 cells in vitro and in vivo
a Volcano plots analyzing differential expressions of mRNA in U87 cells. Green dots represent downregulated genes, and red dots represent upregulated genes. b Histogram showing the differentially expressed mRNA in U87 cells, 158 genes were upregulated, and 204 genes were downregulated. c Differentially expressed mRNA on the top 20 pathways identified by KEGG analysis. Bubble size represents the number of DEGs enriched in a signaling pathway; the bubble color represents the q value. d GO enrichment analysis of the significantly upregulated and downregulated genes. Red columns are the numbers of up-regulated DEGs related to this function, and green columns are the numbers of down-regulated DEGs; DEGs were chosen by a fold change ≥ 2 and q < 0.01.
