Fig. 5: Decreased inflammation level in NCTD-treated MRL/lpr mice. | Acta Pharmacologica Sinica

Fig. 5: Decreased inflammation level in NCTD-treated MRL/lpr mice.

From: Norcantharidin ameliorates the development of murine lupus via inhibiting the generation of IL-17 producing cells

Fig. 5: Decreased inflammation level in NCTD-treated MRL/lpr mice.

a Heatmap of the inflammation cytokine level in MRL/MpJ and MRL/lpr mice evaluated by Bio-Plex ProTM Mouse Cytokine 23-plex Assay. n = 3 (MRL/MpJ group) or 4 (MRL/lpr group). b–g The levels of cytokines (IFN-γ, IL-4, IL-10, IL-17, IL-22, and IL-23) in serum were determined with ELISA. n = 3 (MRL/MpJ group) or 4 (MRL/lpr group). *P < 0.05, **P < 0.01, MRL/lpr + vehicle vs. MRL/MpJ + vehicle; $P < 0.05, MRL/lpr + NCTD (1 mg/kg) vs. MRL/lpr + vehicle; #P < 0.05, ##P < 0.01, MRL/lpr + NCTD (2 mg/kg) vs. MRL/lpr + vehicle.

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