Fig. 1: Chemical structure of the lipophilic compound cynaropicrin and the cytotoxic effect of cynaropicrin in nine different human multiple myeloma (MM) cell lines (AMO1, KMS11, JJN3, MolP8, L363, NCI-H929, RPMI8226, OPM2, and KMS12BM), in human AML cells (CCRF/CEM, CEM/ADR5000), and PBMCs. | Acta Pharmacologica Sinica

Fig. 1: Chemical structure of the lipophilic compound cynaropicrin and the cytotoxic effect of cynaropicrin in nine different human multiple myeloma (MM) cell lines (AMO1, KMS11, JJN3, MolP8, L363, NCI-H929, RPMI8226, OPM2, and KMS12BM), in human AML cells (CCRF/CEM, CEM/ADR5000), and PBMCs.

From: Cynaropicrin disrupts tubulin and c-Myc-related signaling and induces parthanatos-type cell death in multiple myeloma

Fig. 1

Each concentration is obtained by calculating the mean value ± SD of three experiments performed at different time points with six replicates in each experiment. a Using a wide concentration range ten-fold apart from 10−7 to 102, b Using a narrower concentration range three-fold apart from 10−2.35 to 102.

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