Fig. 1: NGR1 relieves the symptoms of colitis mice caused by DSS.

a The drawing chart presented the animal experimental procedure. b Changes in body weight in mice of each group. The data were plotted as a percentage of the weight at baseline. Each bar represents the mean ± SD (n = 6 per group). (c) The occurrence of bloody diarrhea. The data are plotted as a percentage of the total mice that had bloody diarrhea at different time points. Each bar represents the mean ± SEM (n = 6 per group). (d, e) Colonic-length changes in mice of each group. f Colonic pathological injury was examined by H&E staining. Scale bar = 50 μm. g Histology scores were counted and presented. Each bar represents the mean ± SD (n = 3 per group). ###P < 0.001 vs. Control group; *P < 0.05, **P < 0.01, ***P < 0.001 vs. DSS group.