Fig. 1: Development of an OSCC prognostic model based on intratumoral microbiota.
From: Intratumoral microbiota drive immune evasion and disease progression in oral squamous cell carcinoma
A LASSO model λ selection via fivefold cross-validation. Dotted lines indicate minimum and 1-SE criteria. B Coefficient profiles of 19 bacteria showing shrinkage toward zero with increasing penalty. C We obtained the best risk score value (17 out of 19 prognosis-related microorganisms) corresponding to each sample for subsequent correlation analysis. D, E Kaplan–Meier curves comparing OS between high- and low-risk groups in training/testing cohorts. F, G Time-dependent ROC curves with 1-, 3-, and 5-year AUCs for training/testing sets.
