Table 1 Key characteristics of included studies.

From: Environmental impact of dental amalgam and alternative restorative materials: a systematic review

Study [Country]

Study design

Setting

Restorative material [Activity]

Category

Al-Kawas 2008 [United Arab Emirates]: JAP [25]

Cross-sectional with comparator

Clinic

Amalgam, composite, glass-ionomer [Restorations, removals]

Mercury levels in wastewater

Binner 2022 [Ireland]; JAP [26]; Harding 2022 [Ireland] GLR [24]

Cross-sectional

Clinic

Composite, glass-ionomer, resin-modified glass ionomer cements [NR]

Animal toxicity of restorative materials

Duane 2017 [UK]; JAP [27]

Secondary analysis of dataset

Clinic

Amalgam, composite, glass-ionomer [Restorations]

Carbon footprint of restorative materials

Gioda 2007 [USA]; JAP [28]

Before and after study

Clinic and lab

Amalgam [Restorations, removals]

Mercury levels in vapour

Kim 2018 [South Korea]; JAP [29]

Cross-sectional

Clinic

Amalgam [Incineration]

Mercury levels in emissions

Kontogianni 2008 [Greece]; JAP [30]

Cross-sectional survey

Clinic

Amalgam [NR]

Mercury levels in solid waste

Majstorovic 2024 [Croatia]; JAP [31]

Cross-sectional (clinic setting) and controlled trial (lab-based)

Part 1: clinic; part 2: lab

Part 1: NR [NR]; Part 2: Commercial composite, glass-ionomer, laboratory-prepared composite, alkasite, amalgam [Leaching]

Animal toxicity of restorative materials

Mandalidis 2008 [Greece]; JAP [32]

Cross-sectional

Clinic

Amalgam [Restorations, removals]

Mercury levels in solid waste

Marquardt 2009 [Germany]; JAP [33]

Cross-sectional

Clinic

Composite [Restorations]

Monomer levels in emissions

Mourouzis 2022 [Greece]; JAP [34]

Controlled trial

Clinic and lab

Composite, polymer infiltrated ceramic CAD/CAM [Restorations]

Monomers levels in wastewater

Olivera 2020 [USA]; JAP [35]

Prospective longitudinal

Clinic

Amalgam [Restorations]

Mercury levels in wastewater and in solid waste

Paryag 2010 [Trinidad and Tobago]; JAP [36]

Modelling study

Lab

Amalgam [Removals]

Mercury levels in wastewater

Piagno 2020 [Canada]; JAP [37]

Modelling study

Crematorium

Amalgam [Incineration]

Mercury levels in emissions

Polydorou 2023 [Germany]; JAP [38]

Controlled trial

Lab

Composite [Dental grinding procedures]

Monomer levels in wastewater

Shraim 2011 [Saudi Arabia]; JAP [39]

Prospective longitudinal with comparator

Clinic

Location 1&2: Amalgam or composite [Restorations], glass ionomer [endodontic treatment]; Location 3a + 3b:Amalgam, composite or glass-ionomer [Restorations]; Location 3c: Composite [Restorations]

Mercury levels in wastewater

Simu 2014 [Romania]; JAP [40]

Cross-sectional

Clinic

Amalgam, composite, glass-ionomer [ultrasound scaling, root canal preparation, cavity preparation and filling, removal of silver amalgam, composite, glass-ionomer filings, teeth preparation for prosthetic purpose, orthodontic controls, etc.]

Mercury levels in particulate matter

Stone 2009 [USA]; JAP [41]

Prospective longitudinal with control

Clinic and lab

Dental amalgam [NR]

Mercury levels in wastewater

Takaoka 2010 [Japan]; JAP [42]

Modelling study

Crematorium

Amalgam [Incineration]

Mercury levels in emissions

Van Landuyt 2014 [Belgium]; JAP [43]

Controlled trial

Clinic and lab

Composite [grinding material to simulate abrasive procedures, including restorations]

Monomer levels in particulate matter

Warwick 2013 [Canada]; JAP [45]

Controlled trial (lab based)

Lab

Amalgam [Removals]

Mercury levels in vapour

Warwick 2019 [Canada]; JAP [44]

Prospective longitudinal with control

Clinic

Amalgam [Removals]

Mercury levels in vapour

  1. GLR grey literature report, JAP journal article publication, NR not reported (several studies do not report the type of dental activity which was carried out, and one study does not report the type of material which was used), USA United States of America.