Fig. 1: Targeted sequencing identifies chromosome-level, arm-level, and focal CNVs. | Blood Cancer Journal

Fig. 1: Targeted sequencing identifies chromosome-level, arm-level, and focal CNVs.

From: A multiple myeloma-specific capture sequencing platform discovers novel translocations and frequent, risk-associated point mutations in IGLL5

Fig. 1

a Hyperdiploid and (b; arrow) focal copy number events detected by CopyCat2 (blue; p < 0.05) from log2 ratios of tumor to paired normal sequencing depth (y-axis) across chromosomes (x-axis). (Clonal) single-copy gains occur at a log2 ratio of log2(3/2)  =0.58, whereas (clonal) heterozygous/single-copy losses occur at a log2 ratio of log2(1/2) = −1

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