Table 3 Highest degree treatment-related adverse events per patient, by renal function group and dose level
Highest degree treatment-related | ||||||||
|---|---|---|---|---|---|---|---|---|
Group | Dose level | Pts | None | 1 | 2 | 3 | 4 | 5 |
A | 1 | 6 | 3 | 2 | 1 | |||
2 | 3 | 1 | 1 | 1 | ||||
3 | 6 | 1 | 1 | 4 | ||||
Expansion | 14 | 1 | 4 | 3 | 6 | |||
B | 1 | 3 | 1 | 1 | 1 | |||
2 | 3 | 1 | 1 | 1 | ||||
3 | 3 | 1 | 1 | 1 | ||||
4 | 8 | 1 | 1 | 2 | 3 | 1 | ||
Expansion | 2 | 1 | 1 | |||||
C | 1 | 3 | 3 | |||||
2 | 3 | 1 | 1 | 1 | ||||
3 | 3 | 2 | 1 | |||||
4 | 5 | 2 | 3 | |||||
TOTAL | 62 | 14 | 11 | 8 | 23 | 5 | 1 | |
