Table 1 Correlation between expression of RBFOX2 and inclusion of exons in RBFOX2 target genes

From: RBFOX2 and alternative splicing in B-cell lymphoma

 

MALT1 exon 7

CLSTN1 exon 11

FMNL3 exon 26

MYO9B exon 37

 

Correlation

p-value

Correlation

p-value

Correlation

p-value

Correlation

p-value

DLBCL ABC (n = 26)

0.496

0.009

0.450

0.023

0.139

0.496

0.338

0.09

DLBCL GCB (n = 37)

0.591

0.0001

0.147

0.383

0.558

0.0004

0.561

0.0003

DLBCL type III (n = 15)

0.125

0.675

0.385

0.156

1

0

0.307

0.265

All DLBCL (n = 78)

0.522

1.2 x 10−6

0.303

0.007

0.300

0.008

0.566

1.1 x 10−7

BL (solid ped BL) (n = 21)

0.703

0.0005

0.669

0.001

0.484

0.027

0.672

0.001

FL (n = 87)

0.321

0.003

0.437

2.3 x 10−5

0.227

0.034

0.397

0.0001

FL-DLBCL (n = 15)

0.464

0.083

0.029

0.923

0.503

0.058

0.435

0.106

GC B cells, control (n = 5)

−0.9

0.083

0.2

0.783

0.3

0.683

−0.2

0.783

Naive B cells, control (n = 5)

0.6

0.083

-0.354

0.783

-0.8

0.683

−0.2

0.783

  1. RNASeq data from lymphoma and control, mapped to hg38 with segemehl 2.0; data were normalized against target
  2. gene expression. Bold: statistically significant. Normalization: transformation to target gene expression levels
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