Table 2 Evolution of the laboratory values after stopping imatinib or nilotinib
At baseline | At 6 months after discontinuation | |||||
|---|---|---|---|---|---|---|
Imatinib | Nilotinib | P | Imatinib | Nilotinib | P | |
Hb, g/dLa | 12.5 (11.7–13.7) | 13.5 (12.5–14.8) | 0.002 | 13.5 (12.7–14.3) | 13.6 (12.4–14.8) | 0.74 |
Leukocytes, × 109/La | 5.4 (4.5.6.9) | 7.8 (6.1–9.1) | < 0.001 | 6.5 (5.4–8) | 7.25 (6.1–9.1) | 0.11 |
Lymphocytes, × 109/La | 1.8 (1.5–2.3) | 2 (1.6–2.4) | 0.063 | 2.1 (1.75–2.6) | 1.85 (1.6–2.5) | 0.18 |
Platelets, × 109/La | 215 (190–257) | 223 (180–269) | 0.59 | 255 (205–286) | 214 (181–271) | 0.09 |
Creatinine, mg/dLa | 0.97 (0.8–1.17) | 0.86 (0.72–1.05) | 0.025 | 0.9 (0.73–1.08) | 0.89 (0.72–1.05) | 0.67 |
Total cholesterol, mg/dLa | 181 (155–203) | 206 (160–238) | 0.025 | 207 (178–232) | 172 (140–210) | 0.004 |