Table 2 Multiple linear regression analyses with stage of disease as an independent variable and different outcome variables

From: Patients with precursor disease exhibit similar psychological distress and mental HRQOL as patients with active myeloma

Variable

HRQOL (PCS)

HRQOL (MCS)

Distress score

Anxiety score

Depression score

B [95%-CI]

P

B [95%-CI]

P

B [95%-CI]

P

B [95%-CI]

P

B [95%-CI]

P

Charlson index

−2.21 [−4.37; −0.06]

.04*

−3.79 [−6.16; −1.42]

.002*

0.48 [−0.10; 1.06]

.1

0.88 [−0.03; 1.79]

.06

1.54 [0.61; 2.47]

.001*

Age

−0.31 [−0.76; 0.14]

.17

0.57 [0.08; 1.07]

.02*

−0.14 [−0.26; −0.02]

.02*

−0.17 [−0.37; 0.02]

.07

−0.09 [−0.28; 0.10]

.37

Sex

−0.05 [−1.91; 1.81]

.96

3.53 [1.49; 5.57]

<.001*

−0.39 [−0.89; 0.11]

0.13

−0.57 [−1.36; 0.22]

.91

−0.70 [−1.50; 0.10]

.09

Stage of myeloma

New diagnosis of MM

−2.63 [−5.09; −0.17]

.04*

1.39 [−1.31; 4.09]

.31

0.06 [−0.61; 0.72]

.87

0.28 [−0.77; 1.33]

0.6

0.01[−1.05; 1.07]

.98

Treated MM

−5.76 [−8.25; −3.27]

<.001*

−0.17 [−2.91; 2.56]

.9

−0.34 [−1.01; 0.34]

.33

0.06 [−1.00; 1.12]

.91

1.30 [0.22; 2.38]

.02*

Hb

0.91 [0.40; 1.41]

<.001*

0.41 [−0.14; 0.97]

.14

−0.21 [−0.35; −0.08]

.002*

−0.12 [−0.33; 0.09]

.27

−0.22 [−0.43; 0.00]

.05*

  1. MM multiple myeloma, HRQOL health-related quality of life, PCS physical component score, MCS mental component score, Hb hemoglobin
  2. Charlson-Index reference: ≤2; age reference: 5-year increase; sex reference: female; stage of myeloma reference: monoclonal gammopathy of undetermined significance/smoldering myeloma