Table 2 Frequency of IgH translocations, hyperdiploidy, and copy number variations and comparison between race
Gene | Type | ALL, n (Nā=ā68) | CA, n (Nā=ā47) | % (n/N) | AA, n (Nā=ā21) | % (n/N) | P-value* |
|---|---|---|---|---|---|---|---|
4;14 | Translocation | 2 | 2 | 4.3 | 0 | 0 | 1 |
8;14 | Translocation | 2 | 2 | 4.3 | 0 | 0 | 1 |
11;14 | Translocation | 6 | 0 | 0 | 6 | 28.6 | 0.0005 |
14;16 | Translocation | 1 | 0 | 0 | 1 | 4.8 | 0.309 |
Hyperdiploidy | Chromosomal gain | 34 | 24 | 51.1 | 10 | 47.6 | 1 |
amp(1q) | Amplification | 13 | 6 | 12.8 | 7 | 33.3 | 0.091 |
del(1p) | Amplification | 3 | 0 | 0 | 3 | 14.3 | 0.027 |
del(13q) | Amplification | 21 | 15 | 31.9 | 6 | 28.6 | 1 |
del(17p) | Amplification | 13 | 10 | 21.3 | 3 | 14.3 | 0.74 |