Table 1 International Myeloma Working Group (IMWG) best response (ITT population)
Response | Overall (n = λ 59) | Best response cycle 1–3 or before addition of CY (n = 59) | Best response under POM + CY + DEX (n = 36) | Best response under POM + CY + DEX according to response at start CY | ||
|---|---|---|---|---|---|---|
Minimal response at start CY (n = 5) | Stable disease at start CY (n = 15) | Progressive disease at start CY (n = 16) | ||||
Objective response rate (≥PR), n (%) | 23 (39.0%) | 11 (18.6%) | 13 (36.1%) | 4 (80.0%) | 5 (33.3%) | 4 (25.0%) |
Partial response, n (%) | 14 (23.7%) | 9 (15.2%) | 8 (22.2%) | 3 (60.0%) | 2 (13.3%) | 3 (18.8%) |
Very good partial response, n (%) | 7 (11.9%) | 2 (3.4%) | 3 (8.3%) | 1 (20.0%) | 1 (6.7%) | 1 (6.2%) |
Complete response, n (%) | 2 (3.4%) | 0 (0%) | 2 (5.6%) | 0 | 2 (13.3%) | 0 |
Minimal response, n (%) | 16 (27.1%) | 12 (20.3%) | 10 (27.8%) | 1 (20.0%) | 4 (26.7%) | 5 (31.2%) |
Stable disease, n (%) | 13 (22.0%) | 23 (39.0%) | 12 (33.3%) | 0 | 6 (40.0%) | 6 (37.5%) |
Progressive disease, n (%) | 5 (8.5%) | 11 (18.6%) | 0 | 0 | 0 | 0 |
Early deatha, n (%) | 2 (3.4%) | 2 (3.4%) | 1 (2.8%) | 0 | 0 | 1 (6.2%) |
