Fig. 2 | Blood Cancer Journal

Fig. 2

From: Characterization of TCF3 rearrangements in pediatric B-lymphoblastic leukemia/lymphoma by mate-pair sequencing (MPseq) identifies complex genomic rearrangements and a novel TCF3/TEF gene fusion

Fig. 2The alternative text for this image may have been generated using AI.

Genomic studies from patient 18, including a representative interphase cells showing a diminished TCF3 signal suggesting a partial deletion or rearrangement of TCF3, using the TCF3/PBX1 D-FISH probe set. b Metaphase FISH demonstrating the diminished TCF3 signal is retained on chromosome 19p. c Representative karyogram with chromatin of undetermined origin attached to 19p. d MPseq junction plot demonstrating a TCF3/ZNF384 fusion

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