Table 1 Patient characteristics
From: EASIX for prediction of survival in lower-risk myelodysplastic syndromes
Cohort | ||||||||
|---|---|---|---|---|---|---|---|---|
Training Heidelberg | Validation Dusseldorf | |||||||
Total | 193 | 333 | ||||||
Risk groupa | Lower | Higher | Lower | Higher | ||||
n/ % | 132 | 68% | 60 | 32% | 255 | 77% | 78 | 23% |
Sex male | 82 | 62% | 34 | 57% | 150 | 59% | 50 | 64% |
Blasts ≥ 10% | 8 | 6% | 46 | 77% | 3 | 1% | 54 | 69% |
Transfusions | 29 | 22% | 25 | 42% | 143 | 56% | 58 | 74% |
Median | Range | Median | Range | Median | Range | Median | Range | |
Age | 70 | 33–84 | 73 | 47–86 | 70 | 20–91 | 71 | 47–84 |
LDH | 222 | 100–670 | 287 | 117–992 | 214 | 105–881 | 224 | 155–542 |
Platelets | 164 | 10–825 | 74 | 9–519 | 142 | 6–648 | 80 | 16–714 |
Creatinine | 0.9 | 0.5–8.2 | 0.9 | 0.5–2.2 | 0.9 | 0.5–4.3 | 1.0 | 0.6–1.9 |
Hemoglobin | 10.0 | 5.0–16.4 | 9.1 | 5.9–12.3 | 10.2 | 6.0–15.4 | 9.5 | 3.7–13.4 |
ANC | 2,2 | 0.2–12.3 | 1.0 | 0–10.5 | 2.1 | 0.1–33.4 | 1.1 | 0.1–8.1 |
EASIX | 1.2 | 0.1–65.0 | 3.3 | 0.3–47.7 | 1.6 | 0.2–130.2 | 3.0 | 0.2–188.6 |
