Table 3 Multivariate analysis.

From: Gain of Chromosome 1q is associated with early progression in multiple myeloma patients treated with lenalidomide, bortezomib, and dexamethasone

  

N

Hazard ratio (95% CI)

HR P-value

Calcium

>10.5

16

2.34 (1.04–5.28)

0.04

≤10.5

148

Ref

Maintenance

Yes

155

0.45 (0.22–0.92)

0.029

No

40

Ref

t(4;14)

Yes

9

4.18 (1.46–11.96)

0.008

No

184

Ref

t(14;16)

Yes

9

2.80 (1.07–7.34)

0.036

No

182

Ref

del(17p)

Yes

24

2.52 (1.25–5.09)

0.01

No

173

Ref

Gain(1q)

Yes

94

1.92 (1.14–3.25)

0.015

No

107

Ref

  1. Number of observations in the original data set = 201. Number of observations used = 149. Backward selection with an alpha level of removal of 0.10 was used. The following variables were removed from the model: Complex Karyotype and del(13q)