Table 2 Hematologic, renal, and cardiac response and progression rates.
Old criteria (per protocol) | New criteria | |
|---|---|---|
Hematologic | ||
N | 92 | 92 |
Responders | 48 (52%) | 57 (62%) |
CR | 6 | 15 |
VGPR | 12 | 22 |
PR | 30 | 20 |
Renal | ||
N | 62 | 62 |
Responders | 15 (24%) | 31 (50%) |
Time to response, median (range) | 161 days (28–502) | 62 days (28–480) |
Progression | 14 (23%) | 27 (44%) |
Time to progression, median (range) | 196 days (21–1022) | 144 days (26–1230) |
Cardiac | ||
N | 71 | 71 |
Responders | 11 (15%) | 6 (8%) |
Time to response, median (range) | 213 days (58–995) | 196 days (35–510) |
Progression | 10 (14%) | 19 (25%) |
Time to progression, median (range) | 232 days (84–697) | 30 days (23–396) |
